Abstract
One of the urgent tasks in modern medicine is the development of innovative treatment regimens with high clinical efficacy. In recent years, a distinctive feature of modern pharmaceutical economics is the choice of methods of analysis, which allows to conduct a cross-assessment of the effectiveness of drugs, costs and identify the most clinically and economically feasible schemes of therapy. The use of proton pump inhibitors (PPI) and prokinetic drugs as a means of primary therapy of acid-dependent pathologies has a number of advantages over other schemes of treatment of pathologies in the gastroduodenal area.