RISK OF FORMING PARKINSON'S DISEASE AT THE EARLY STAGES

Abstract

The article presents the results of observation of 213 patients with PD, including 90 (42.25%) women, 123 (57.75%) men. Patients with PD were selected in accordance with the international criteria of the British Brain Bank “Parkinson's Disease Society Brain Bank". A comprehensive assessment of the general condition of patients, as well as the diagnosis of PD, was carried out in order to identify factors affecting the progression of PD in general: determination of the main unmodifiable risk factors and non-motor manifestations of PD progression, clinical neurological studies, laboratory research methods, neuropsychological studies, magnetic resonance imaging (MRI), electroencephalography (EEG).The results of the study showed that the identification of early biomarkers of the premotor phase of the disease is important for early diagnosis and treatment and their predictive significance in the progression of PD.