Keywords
cellular and humoral immunity, photodynamic therapy, chronic suppurative otitis media
Abstract
The effectiveness of standard and combined treatment using photodynamic therapy was evaluated based on the study of the levels of interleukin-2, interleukin-6 and tumor necrosis factor in 84 patients with chronic purulent otitis media. Photodynamic therapy was administered with aqueous solution of methylene blue every other day for 6 days (3 manipulation. It was found that by the end of the course of traditional therapy, a cytokine imbalance persists, indicating ongoing inflammatory changes. The inclusion of photodynamic therapy in the treatment regimen of patients with chronic suppurative otitis media significantly improved cytokine status.