Abstract
The growth of fibroadenomas is thought to be estrogen-dependent: however, none of the steroid hormone receptors acting on breast tissue have been shown to cause fibroepithelial damage in the breast stroma. This article examines estrogen receptor (ER)-α and -β expression in fibroadenomas and benign, three-borderline, and malignant phyllodes tumors by immunocytochemistry. All of these scans revealed spindle-shaped cells and one distant metastasis.