Keywords
Abstract
Currently, there is a high frequency of organic lesions of the peripheral nervous system (PNS) in children associated with both inflammatory and hypoxic -ischemic processes resulting in demyelination and/or degeneration of nerve fibers. The severity of damage to the nervous system, the rapidity of the development of the disease, high mortality and the frequency of disability in children determine the relevance of their study.
Purpose of the study. Assess the significance of clinical and pathogenic determinants in the occurrence of peripheral nervous system disease
Materials and research methods. 100 patients aged from 3 months to 17 years were under observation. The average age of children with PNS diseases is 4.2± 1.5 years . Depending on the duration of the increase in neurological symptoms, among patients with PNS diseases, an acute course was diagnosed, in which there was an increase in symptoms within 3-14 days with a complete reverse regression within 1-2 months; protracted course, in which there were repeated relapses or continuous progression lasting from 2 weeks to 6 months with reverse partial or complete regression within 6-12 months
Research results. The acute onset of the disease with rapid progression of cerebral and / or focal symptoms within 1-4 days was more typical for polyneuritis, and was also noted in 56% of cases with plexitis. Whereas with ganglionitis , the gradual development of the clinical picture was more often noted, over several days, and sometimes weeks. Also, with ganglionitis , in 56.3% of cases, neurological symptoms were observed in children earlier (for several months - up to 2 years), and in 80% (n=64) they regressed in the absence of any treatment. Such symptoms included dizziness and ataxia, blurred vision in one eye, sensory disorders by hemitype . When analyzing outpatient cards and collecting anamnestic data on past infectious diseases in children with polyneuritis, it was found that the most common were chicken pox, otitis media, tonsillitis and / or tonsillitis and intestinal infections, the frequency of which was 72.7%, 45.3%, 44.7% and 36.0%, respectively.
Conclusions: Thus, diseases of the peripheral nervous system of an infectious lesion are of great interest in terms of clinical and neuroimaging data and allow us to differentiate these disorders from neuroinfection , which confirms the relevance of the study.