Keywords
Abstract
In the development of acute pathology of the respiratory organs, not only the
infectious factor is important, but also the initial level of children's health. In turn, the
initial level depends on intrauterine development, intranatal period and background pathology,
in particular, hypoxic-ischemic encephalopathy. A number of researchers have identified a
relationship between CNS damage and the development of bronchopulmonary pathology
[1,4,8]. The aim of the study was to assess the characteristics of the course of obstructive
bronchitis in children with hypoxic-ischemic encephalopathy, depending on premorbid and
environmental factors and immuno-biological indicators. 126 children at an early age with
obstructive bronchitis were examined, who were randomly divided into 3 groups. It has
been established that obstructive bronchitis occurring against the background of hypoxicischemic encephalopathy in young children living in a region with environmentally unfavorable
conditions differ in a number of significant clinical and immuno-biochemical features, the
combination of pathogenic factors of the premorbid soil is of decisive importance in the
formation of which. including a complex of negative endo - and exogenous influences.