Abstract
Background: This study examined the prevalence of Ladd syndrome and the relationship between SL and demographic factors in the Republic of Uzbekistan. Methods: Data were obtained from the medical records of children born with congenital malformations for 5 years (2015–2020) in 13 subjects of the Republic of Uzbekistan. Results: The total number of births was 3,759,310. 3037 cases of congenital malformations were registered, of which malformations of the digestive tract were 1315 children, among which 50 (3.8%) children were diagnosed with SL. In terms of relative risk (RR), the risk of having LS was high in newborns (RR = 1.94; 95% CI 1.47–2.56). The maximum relative risk was observed in newborns with low birth weight (RR=1.25; 95% CI 0.96 - 1.64). Conclusion: This study analyzed the prevalence of SL in various regions of the Republic of Uzbekistan. The prevalence of LS remained stable during the study period, and the relative risk of LS was related to maternal age, birth weight, and severity.