Keywords
Intestinal mucosa,chronic renal insufficiency,morphology,intestinal absorption ,Rat
Abstract
Despite the severe but compensated chronic renal failure that we induced in
rats by 9/10 staged nephrectomy, we did not observe corresponding pathological changes in
the mucosa and intestines. Even in animals that died prematurely from uremia, there were
no signs of erosions, ulcers, or pseudomembranous colitis, which are usually considered
characteristic of the uremic condition. Thus, there are significant doubts about the existence
of "uremic enterocolitis", and these doubts are confirmed after a critical review of the
literature on human pathology.