Abstract
to study hepatic encephalopathy caused by endogenous intoxication in patients
with diabetes mellitus (DM) complicated by necrotic soft tissue lesion (PNSTL) and ways
of their correction. Materials and methods: 58 patients with diabetes mellitus complicated
by purulent-necrotic soft tissue lesion and the effect of endotoxicosis on the functional state
of the liver were examined in the intensive care unit, with optimization of correction of
hepatic encephalopathy. In addition to traditional therapy, hepatoprotectors and drugs
that stop transaminase activity are included in patients. Conclusions. Early detection of
hepatic encephalopathy before clinical manifestations and timely correction is pathogenetically
justified and optimizes the outcomes of such a formidable complication as hepatic
encephalopathy and coma.