Keywords
Abstract
Purpose: comparative evaluation of the Oculus mobile device data on the diagnostic information content of morphometric parameters of the optic nerve head, retinal per papillary nerve fibers and the retinal ganglion cell complex in the early diagnosis and monitoring of primary open-angle glaucoma (POAG).
Methods: The study included both patients with glaucoma and healthy individuals. The examination was carried out with an Oculus mobile device and optical coherence tomography (OCT) was performed on a Cirrus 4000 HD-OCT tomograph. 19 morphometric parameters were evaluated.
Results. A total of 67 people (101 eyes) were examined, of which the control group (healthy individuals) - 22 people (44 eyes), patients with POAG - 45 people (57 eyes) with stages I, II and III of glaucoma.
The most informative parameters in the diagnosis and monitoring of POAG differed. When examined with the Oculus mobile device, changes were observed in dynamics mainly in the temporal and lower segments. The sequence of diagnostic significance of OCT parameters in the diagnosis of glaucoma: global volume loss index (GLV), GCC average thickness (GCC Average), GCC complex thickness in the lower segment (GCC Inferior)). An algorithm for reading OCT results in the early diagnosis of glaucoma is proposed.
The sequence of diagnostic significance of OCT parameters in glaucoma monitoring: the index of the thickness of peripapillary nerve fibers in the lower temporal and upper temporal segments (RNFL IT and ST Thikness) and the average value of the thickness of peripapillary fibers (RNFL Average Thikness). An algorithm for reading OCT results in glaucoma monitoring is proposed.
Conclusion: The use of the Oculus mobile device is of practical importance in the diagnosis of glaucoma and in monitoring over time, as well as in fixing data in the conditions of diagnosis in the primary level of examination. OCT is highly sensitive in both diagnosis and monitoring of glaucoma. The characteristics of the complex of retinal ganglion cells have the maximum information content in early diagnosis. In POAG monitoring, the parameters of the retinal nerve fiber layer are the most informative.