Abstract
Sepsis remains an urgent problem in pediatrics due to high mortality. To date, the problem of laboratory diagnosis of sepsis has not been resolved. The results of a large number of studies conducted in recent years indicate that in the development of purulent-inflammatory diseases, sepsis and other cases of infectious diseases, the level of various opportunistic and saprophytic both aerobic and anaerobic inflammations of the microflora increases [1,2], which has features of the development of the inflammatory process. However, the methods of classical microbiological diagnostics (blood culture), with the isolation of a pure culture of anaerobes, are laborious and not always secondary. Recently, for the diagnosis of anaerobic pyoinflammatory phenomena, the determination of metabolites of anaerobic bacteria, which are low molecular weight compounds and are specific markers that create volatile fatty acids (VFA ), which allow you to quickly and reliably determine a small proportion of microbial inflammation, has been used. including anaerobes in any biological environment of the body and obtaining results . , all of which are specific to strict anaerobes as end products enriched in human cells. The fact of detection of VFAs in biological media and tissues is used to diagnose anaerobic diseases [4,6,8].