https://artofmedicineimsj.us/index.php/artofmedicineimsj <p>Art of Medicine. International Medical Scientific Journal<strong> </strong>is international, open access, double-blinded, peer-reviewed journal published four times per year (January, April, July, and October). Articles are published online when ready for publication as “Articles in Press”. Additional issues may be published for special events.<br /><a href="https://bookwire.com/book/USA/Art-of-Medicine-International-Medical-Scientific-Journal-9780578265100--83737035">ISBN: 978-0-578-26510-0 </a><br />Order your journal <br />price 100$ </p> Published by North American Academic Publishing Platforms en-US Art of Medicine. International Medical Scientific Journal https://artofmedicineimsj.us/index.php/artofmedicineimsj/article/view/250 <p><span class="fontstyle0">Recent decades have been characterized by an increasing trend in the incidence<br>of syphilis throughout the world, with a particularly alarming fact being the increase in<br>latent forms of the disease. The infectious-toxic effect of treponema pallidum on the body<br>can be accompanied by various disorders of the liver, in particular the monooxygenase<br>system (MOS) and affect the state of endogenous intoxication of the body. These disorders<br>can affect both the course of the disease and the quality of specific treatment. Our study<br>showed that patients with latent early syphilis had impaired liver MOS parameters and<br>high endogenous intoxication; after treatment they tended to normalize, but did not return<br>to the control values, which dictates the need to prescribe pathogenetic therapy.</span> </p> A.K. Mangitov K.A. Yuldashev G.B. Pyagai Copyright (c) 2024 Art of Medicine. International Medical Scientific Journal 2024-08-09 2024-08-09 4 1